Research Article
Open Access
Investigating UTI-Related Microbial Pathogens in Pregnancy through Isolation and Diagnostic Identification
Bernacchi Rittmann1*, Hosseini Tafreshi2, Stackebrandt Lima3,4, Maestro Rinaldi3, Hill Fiechter4, Laport Peles2,4
1Department of Food Biotechnology and Microbiology, Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSICUAM), Nicolás Cabrera, 9, 28049 Madrid, Spain
2Fundación Para el Estudio de las Enfermedades Neurometabólicas, Buenos Aires, Argentina
3Department of Clinical Microbiology, IISFundación Jiménez Díaz, UAM. Av. Reyes Católicos, 2, 28040 Madrid, Spain
4Department of Nephrology and Hypertension, IIS-Fundación Jiménez Díaz, UAM. Av. Reyes Católicos, 2, 28040 Madrid, Spain
2Fundación Para el Estudio de las Enfermedades Neurometabólicas, Buenos Aires, Argentina
3Department of Clinical Microbiology, IISFundación Jiménez Díaz, UAM. Av. Reyes Católicos, 2, 28040 Madrid, Spain
4Department of Nephrology and Hypertension, IIS-Fundación Jiménez Díaz, UAM. Av. Reyes Católicos, 2, 28040 Madrid, Spain
Rittmann B, Tafreshi H, Lima S, Rinaldi M, Fiechter H, et al. Investigating UTI-Related Microbial Pathogens in Pregnancy through Isolation and Diagnostic Identification, Accounts of Biotechnology Research. 2024, Vol. 12 No. 1: 101
Abstract
Urinary tract infections (UTIs) remain a significant cause of illness in women and
are particularly concerning during pregnancy due to the potential for complications
affecting both mother and fetus. In children, UTIs are often associated with
nonspecific clinical symptoms, leading to delayed diagnosis and increasing the risk
of long-term outcomes such as renal scarring, hypertension, and chronic kidney
disease. The persistence of undetected or inadequately managed UTIs therefore
represents an important public health challenge.
The present study focuses on the isolation and characterization of bacterial
pathogens responsible for UTIs in both pregnant and non-pregnant women,
followed by antimicrobial susceptibility profiling. Urine samples were collected
from various private hospitals and nursing homes in Noida and processed at
Helix Biogenesis Pvt. Ltd., Noida. A total of 15 participants were included—10
pregnant women constituting the study group and 5 non-pregnant women serving
as controls—representing diverse age categories. The findings were further
compared with data reported in previous studies to highlight regional variability
and resistance trends.
are particularly concerning during pregnancy due to the potential for complications
affecting both mother and fetus. In children, UTIs are often associated with
nonspecific clinical symptoms, leading to delayed diagnosis and increasing the risk
of long-term outcomes such as renal scarring, hypertension, and chronic kidney
disease. The persistence of undetected or inadequately managed UTIs therefore
represents an important public health challenge.
The present study focuses on the isolation and characterization of bacterial
pathogens responsible for UTIs in both pregnant and non-pregnant women,
followed by antimicrobial susceptibility profiling. Urine samples were collected
from various private hospitals and nursing homes in Noida and processed at
Helix Biogenesis Pvt. Ltd., Noida. A total of 15 participants were included—10
pregnant women constituting the study group and 5 non-pregnant women serving
as controls—representing diverse age categories. The findings were further
compared with data reported in previous studies to highlight regional variability
and resistance trends.
Keywords
Urinary tract infection; Pregnant women; Microbial isolation; Pathogen identification; Antimicrobial susceptibility.